Hepatocellular carcinoma (HCC): beyond sorafenib—chemotherapy

MRI in detection of hepatocellular carcinoma (HCC)

Hepatocellular carcinoma (HCC) is the commonest malignancy of the liver and is usually due to cirrhosis. Early detection of HCC and the premalignant dysplastic nodules has implications on the management options of tumor ablation, liver resection and transplantation. Magnetic resonance imaging is useful for the detection and characterization of lesions, in the identification of dysplastic nodule...

Clinical biomarkers in hepatocellular carcinoma (HCC).

The Authors make a review of the most important molecules used today for detecting and screening hepatocellular carcinoma, analyzing their known biological features, advantages and limits especially concerning differential diagnosis from cirrhosis and others diseases. AFP, AFP-L3, DCP, Alpha-1-fucosidase are analyzed and all the current knowledge reviewed, as well as focusing on possible future...

Hepatocellular carcinoma (HCC) and diagnostic significance of A-fetoprotein (AFP).

BACKGROUND Alpha-fetoprotein (alpha-fetoprotein, AFP) is a Glycoprotein, belonging to the intriguing class of onco-development protein. Generally designated as tumour marker, AFP is recognized as an important blood component, having specific diagnostic utilities Elevation of its level up to pathological range in adults correlate with the appearance of several malignant and chronic conditions, s...

Medical treatments for hepatocellular carcinoma (HCC): what's next?

Hepatocellular carcinomas (HCC) is the fifth most common malignancy worldwide. HCC incidence has doubled over the last 20 years in Europe [1]. This is probably related both to the improvement of life expectancy in cirrhotic patients and the increased incidence of cirrhosis due to viral hepatitis C. HCC incidence greatly varies across Europe from 14/100 000 men/year in Italy to 1.7/100 000 men/y...

Hepatocellular Carcinoma in Sheep